Physiological assessment of paroxysmal dystonia secondary to subacute sclerosing panencephalitis
Identifieur interne : 004347 ( Main/Exploration ); précédent : 004346; suivant : 004348Physiological assessment of paroxysmal dystonia secondary to subacute sclerosing panencephalitis
Auteurs : William G. Ondo [États-Unis] ; Amit Verma [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2002-01.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adult, Brain (metabolism), Carbamazepine, Case study, Chemotherapy, Complication, Dibenzazepine derivatives, Dystonia, Dystonia (diagnosis), Dystonia (etiology), Electroencephalography, Fatal Outcome, Female, Humans, Sclerosing panencephalitis, Severity of Illness Index, Single photon emission tomography, Subacute, Subacute Sclerosing Panencephalitis (complications), Tomography, Emission-Computed, Single-Photon, Treatment, Tricyclic compound, Young adult, carbamazepine, myoclonus, paroxysmal dystonia, subacute sclerosing panencephalitis.
- MESH :
- complications : Subacute Sclerosing Panencephalitis.
- diagnosis : Dystonia.
- etiology : Dystonia.
- metabolism : Brain.
- Adult, Electroencephalography, Fatal Outcome, Female, Humans, Severity of Illness Index, Tomography, Emission-Computed, Single-Photon.
Abstract
We report on a 26‐year‐old woman with subacute sclerosing panencephalitis (SSPE) who presented with frequent paroxysmal dystonic posturing. Electroencephalogram demonstrated generalized 5 to 10‐second episodes of high‐amplitude (150–300 μV) delta activity alternating with 10 to 20‐second periods of theta activity (40–50 μV). The patient experienced episodes of dystonic posturing coinciding with the periods of delta activity. Ictal Tc‐99m Ceretec SPECT demonstrated marked increased activity in the bilateral caudate (R>L). The frequency and amplitude of the episodes initially markedly improved after the addition of carbamazepine. We suggest that the movements seen in this case of SSPE may represent basal ganglia ictal activity. © 2001 Movement Disorder Society.
Url:
DOI: 10.1002/mds.10005
Affiliations:
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Le document en format XML
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<term>Case study</term>
<term>Chemotherapy</term>
<term>Complication</term>
<term>Dibenzazepine derivatives</term>
<term>Dystonia</term>
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<term>Dystonia (etiology)</term>
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<term>Complication</term>
<term>Composé tricyclique</term>
<term>Dibenzo azépine dérivé</term>
<term>Dystonie</term>
<term>Electroencéphalographie</term>
<term>Etude cas</term>
<term>Femelle</term>
<term>Panencéphalite sclérosante</term>
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<front><div type="abstract" xml:lang="en">We report on a 26‐year‐old woman with subacute sclerosing panencephalitis (SSPE) who presented with frequent paroxysmal dystonic posturing. Electroencephalogram demonstrated generalized 5 to 10‐second episodes of high‐amplitude (150–300 μV) delta activity alternating with 10 to 20‐second periods of theta activity (40–50 μV). The patient experienced episodes of dystonic posturing coinciding with the periods of delta activity. Ictal Tc‐99m Ceretec SPECT demonstrated marked increased activity in the bilateral caudate (R>L). The frequency and amplitude of the episodes initially markedly improved after the addition of carbamazepine. We suggest that the movements seen in this case of SSPE may represent basal ganglia ictal activity. © 2001 Movement Disorder Society.</div>
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